Evaluation of ABO And RH Blood Groups Among Helicobacter Pylori Infection Among Patients Aattending Thika Level 5 Hospital, Kiambu, Kenya

Abstract

Abstract

 Background: Blood group A and B carbohydrate are thought to impact the risk of getting H. pylori through sticking to the gastric mucosa in the crypts. Knowing the risk factors connected with the infection, interventions and guidance on appropriate preventative measures are required.

Methods: The study included 201 patients with dyspepsia symptoms referred from outpatient department for investigation between age 16-75 years. Data on demographic information was gathered before they were given questionnaires. All patients were investigated for blood group phenotype and rhesus dependent through slide hemagglutination test. H. pylori stool antigen test was also conducted for its positivity. The data was analyzed using SPSS version 25.

Results: The frequency of ABO and Rhesus blood group among H. pylori infected patients was   O, A, B, AB (48.2%), (31.8%), (14.1%), (5.9%) respectively. The majority of the patient were female 51 and 34 males.

Conclusion: H. pylori infection is an endemic problem that needs to be addressed by improving hygiene, providing purified water and taking additional steps for its eradication. Blood type O are more likely to contract H. pylori infections while female and younger adults are more prone to the disease.

Key words: H. pylori infection, ABO blood groups, dyspepsia.